It is a widely used combination medicine in India, known for its quick and reliable relief from various types of pain and fever. Whether it’s a headache, toothache, muscle pain, or body ache from fever, it has been a go-to remedy for many households for decades.
In this article, let’s understand everything about Combiflam Tablet: its composition, uses, how it works, substitutes, FAQs, and precautions — all in a simple, human-friendly way

Table of Contents
Combiflam: Uses, works, Side Effects & Substitutes, FAQs and more
What is Combiflam Tablet?
It is a doctor-recommended medication formulated with two powerful active components working together for better relief.
Ibuprofen (400 mg) – A non-steroidal anti-inflammatory drug (NSAID) that reduces inflammation and relieves pain.
Paracetamol (325 mg) – Also known as acetaminophen, it works mainly to reduce fever and mild to moderate pain.
Together, these two ingredients provide dual-action relief from both pain and fever more effectively than either medicine alone.
Main Uses of Combiflam Tablet:
It helps manage several everyday health issues, especially those involving pain, inflammation, or elevated body temperature, such as:
Headache & Migraine
Fever
Toothache
Muscle pain or cramps
Back pain
Arthritis-related joint pain
Menstrual cramps
Post-surgical pain
This tablet is beneficial when the pain is accompanied by swelling or inflammation.

How Does Tablet Combiflam Work?
Ibuprofen helps reduce discomfort by stopping the release of certain natural substances (prostaglandins) in the body that trigger pain, swelling, and inflammation.
Paracetamol acts on the brain’s heat-regulating center to lower body temperature and relieve mild pain.
This combination provides fast and long-lasting relief from discomfort and brings down fever effectively.
Dosage and Safety Guidelines:
Always take it after food to avoid stomach irritation.
Do not exceed 3 tablets per day unless advised by your doctor.
Avoid taking it continuously for more than 3 days without medical supervision.
Important: Never self-medicate, especially in case of long-term pain. Consult your doctor before starting or continuing the use of it.
Substitutes of Combiflam Tablet:
Here are some popular alternatives that contain a similar combination of Ibuprofen and Paracetamol:
Ibugesic Plus
Brufen Plus
Flexon Tablet
Ibumol Tablet
Pacimol-IB
⚠️ Note: Though these are substitutes, dosage and suitability vary, so always consult your doctor or pharmacist before switching.

Who Should Avoid Combiflam?
Do not take it if you:
- Are allergic to ibuprofen, paracetamol, or NSAIDs
- Have a history of gastric ulcers, bleeding, or acidity
- Have severe liver or kidney problems
- Are pregnant (especially 3rd trimester) or breastfeeding, unless prescribed
- Have asthma triggered by NSAIDs
Always consult your doctor before use, especially if you’re on other medications.
Also read: Susten 200 Tablet – Complete Guide on Uses, Dosage & FAQs for hormonal support during pregnancy.
Frequently Asked Questions (FAQs)
Q1. Can I take Combiflam on an empty stomach?
Q2. Is Combiflam safe during pregnancy?
Q3. Can I take it daily?
Q4. Is it a painkiller or an antibiotic?
Q5. Does it cause drowsiness?
Conclusion
Combiflam is a fast-acting dual-action tablet designed to quickly ease pain and bring down fever, offering reliable comfort when you need it most. It’s widely used, trusted, and easily available — but like all medicines, it should be used responsibly and under medical advice.
Whether it’s a sudden headache or post-surgical pain, it offers quick comfort. But remember, pain is a signal from your body — always listen to it and consult a doctor if it persists.